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Preclinical Alzheimer's risk from brain MRI.

Earlia One is a privacy-preserving, explainable desktop workflow for brain MRI. Run preclinical Alzheimer's risk analysis on your own machine, inspect attention overlays in 3D, and export a reviewable PDF report.

Earlia One desktop application showing a 3D brain MRI with a spatial attention overlay
Local
Inference on your machine
3D
Brain visualization & attention
PDF
Reviewable reports
Win · macOS · Ubuntu
Native desktop app
Capabilities

3D visualization, explainable attention, full transparency

Every prediction is inspectable. Every output is exportable. Nothing leaves your machine unless you choose to send it.

3D brain visualization

Interactive 3D viewer for brain MRI volumes. Rotate, zoom, and inspect from any angle.

Attention mapping

See exactly which brain regions the model focused on, with interactive 3D attention overlays.

Privacy-preserving

All inference runs locally. Patient data stays on your machine or inside your network depending on deployment.

Automated PDF reports

Model outputs, confidence scores, attention snapshots, and a clinician-reviewable draft narrative — exported as PDF.

GPU accelerated

Maximum-speed inference on your existing hardware, with CPU fallback when GPUs aren't available.

Pluggable models

Choose between a 3D-RVN baseline and a Semi-Transformer higher-accuracy model for the same preclinical risk task. More on the roadmap.

Workflow

From scan to preclinical risk in minutes

Three simple steps. No cloud round-trip. No browser tabs. No new account.

01

Load a brain scan

Drag and drop a brain MRI file, or select from sample scans bundled with the app.

02

Visualize & analyze

Inspect the 3D brain and click Analyze to run local inference using the 3D-RVN baseline or the Semi-Transformer model.

03

Understand & export

Inspect attention regions, review scores, and export a PDF report with visual evidence ready for clinician or researcher review.

Product

Built for clinical and research workflows

No browser tabs, no account creation, no learning curve.

Earlia One desktop application interface with model output panel

Native desktop app

Runs on Windows, macOS, and Ubuntu. Single-click install.

Clinical & dark themes

Clean light theme for clinical settings, dark theme for reading rooms.

One-click PDF reports

Model outputs, attention maps, and a clinician-reviewable draft narrative — exported as PDF.

Model selection

Choose between two preclinical Alzheimer's models: 3D-RVN (baseline) and Semi-Transformer (higher accuracy).

Peer-reviewed research

Built on a foundation of published science

Earlia One began as peer-reviewed research showing that subtle neuroanatomical patterns in 3D brain MRI — well before clinical symptoms — can be used to estimate preclinical Alzheimer's risk.

  • Risk of preclinical-stage Alzheimer's disease as the target task.
  • Semi-Transformer architecture with spatial attention for higher accuracy.
  • 3D-RVN baseline model for the same preclinical risk task.
  • Explainable AI: every prediction can be inspected via attention overlays.
  • Validated on established brain MRI datasets (details available on request).
  • Positioned as a research and clinician-review tool, not a standalone diagnostic device.

Explainable, private medical AI — on your own infrastructure.

Visualize, analyze, and export reports without sending patient data off your machine.

Research / clinician-review positioning. Earlia One is intended for research and clinician-assisted review workflows. It is not a standalone diagnostic device. Performance claims, dataset details, and validation results are available on request and should be evaluated against your institution's clinical and regulatory requirements.